PC-61649 |
ONC201
TRAIL inducer, ClpP activator
|
ONC201 (Dordaviprone, TIC10, ONC-201) is a potent, orally active, and brain-permeable small molecule that transcriptionally induces TRAIL in a p53-independent manner, is a potent caseinolytic protease P (ClpP) activator with EC50 of 1.25 uM. |