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首页-小分子抑制剂&激动剂-Apoptosis-TRAIL

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Cat. No. Product Name Information
PC-61649

ONC201

TRAIL inducer, ClpP activator

ONC201 (Dordaviprone, TIC10, ONC-201) is a potent, orally active, and brain-permeable small molecule that transcriptionally induces TRAIL in a p53-independent manner, is a potent caseinolytic protease P (ClpP) activator with EC50 of 1.25 uM.
PC-45466

Bioymifi

DR5 activator

Bioymifi is a potent small-molecule activatior of the TRAIL receptor DR5, directly binds to DR5 with Kd of 1.2 uM.

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