ψTnI | | Probechem Biochemicals

Chemical Structure : ψTnI

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ψTnI (Peptide DWRKNIDA)

货号: PC-20196Not For Human Use, Lab Use Only.

ψTnI (Peptide DWRKNIDA) is a selective, high-affinity, eight amino acid peptide inhibitor of cardiac troponin I (cTnI), directly binds to δPKC with high affinity (Kd=5 nM) and inhibits cTnI/δPKC interaction.

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生物&药学活性

ψTnI (Peptide DWRKNIDA) is a selective, high-affinity, eight amino acid peptide inhibitor of cardiac troponin I (cTnI), directly binds to δPKC with high affinity (Kd=5 nM) and inhibits cTnI/δPKC interaction.
ψTnI selectively inhibits cTnI phosphorylation by δPKC, prevents IR-induced cardiac damage and mitochondrial dysfunction.
ψTnI attenuates IR-induced mitochondrial dysfunction in male rat hearts.

物理化学性质&存储条件

分子量
分子式
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Sequence: Asp-Trp-Arg-Lys-Asn-Ile-Asp-Ala

参考文献

1. Nir Qvit, et al. Pharmaceuticals (Basel). 2022 Feb 22;15(3):271.

ψTnI (Peptide DWRKNIDA)

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物理化学性质&存储条件

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ψTnI (Peptide DWRKNIDA)

生物&药学活性

物理化学性质&存储条件

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