ζ-Stat |CAS:3316-02-7 Probechem Biochemicals

Chemical Structure : ζ-Stat

CAS No.: 3316-02-7

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ζ-Stat (NSC37044, PKC-zeta inhibitor, Zeta-Stat)

货号: PC-35337Not For Human Use, Lab Use Only.

ζ-Stat (1,3,6-Naphthalenetrisulfonic acid) is a novel PKC-zeta (PKC-ζ) specific inhibitor with IC50 of 5 uM, shows only 13% inhibition on PKC-I at 20 uM.

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10 mg	￥3980	In stock
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生物&药学活性

ζ-Stat (1,3,6-Naphthalenetrisulfonic acid) is a novel PKC-zeta (PKC-ζ) specific inhibitor with IC50 of 5 uM, shows only 13% inhibition on PKC-I at 20 uM.
ζ-Stat downregulates TNF-α induced NF-κB translocation to the nucleus there by inducing apoptosis.
ζ-Stat significantly decreases melanoma cell proliferation of SK-MEL-2 and MeWo.

物理化学性质&存储条件

分子量	384.344
分子式	C10H8O10S3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	8-hydroxy-1,3,6-naphthalenetrisulfonic acid

参考文献

1. Islam SMA, et al. Biochim Biophys Acta. 2018 Apr;1865(4):650-664.

2. Ratnayake WS, et al. Cell Adh Migr. 2018 May 21:1-17.

ζ-Stat (NSC37044, PKC-zeta inhibitor, Zeta-Stat)

生物&药学活性

物理化学性质&存储条件

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ζ-Stat (NSC37044, PKC-zeta inhibitor, Zeta-Stat)

生物&药学活性

物理化学性质&存储条件

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