β-catenin-IN-11a |CAS:1884472-26-7 Probechem Biochemicals

Chemical Structure : β-catenin-IN-11a

加入收藏

β-catenin-IN-11a

货号: PC-62707Not For Human Use, Lab Use Only.

β-catenin-IN-11a is a β-catenin/CD44/Nanog axis inhibitor, docks into the β-catenin allosteric site and interferes β-catenin/TCF-4 complex.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

β-catenin-IN-11a is a β-catenin/CD44/Nanog axis inhibitor, docks into the β-catenin allosteric site and interferes β-catenin/TCF-4 complex.
β-catenin-IN-11a blocks the cell cycle inhibitory effect of CD44 and induces cell accumulation of CD44 high cells in cycling phase in S, G2 and M phase, leads to inhibition of embryonic transcriptional factor Nanog but not Sox2 or Oct-4 in colon cancer cells.

物理化学性质&存储条件

分子量	504.59
分子式	C31H28N4O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N'-(1-((benzyl(methyl)amino)methyl)-2-oxoindolin-3-ylidene)-2-(benzyloxy)benzohydrazide

参考文献

1. Radwan AA, et al. Bioorg Med Chem Lett. 2016 Apr 1;26(7):1664-70.

β-catenin-IN-11a

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

β-catenin-IN-11a

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.