β-catenin-BCL9 inhibitor 28

Chemical Structure : β-catenin-BCL9 inhibitor 28

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货号: PC-28110Not For Human Use, Lab Use Only.

β-catenin-BCL9 inhibitor 28 is a potent and selective inhibitor of β-catenin/BCL9 interaction, shows high-affinity binding to β-catenin with SPR Kd of 82 nM, enhances antigen presentation and activates cDC1 cells.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

β-catenin-BCL9 inhibitor 28 is a potent and selective inhibitor of β-catenin/BCL9 interaction, shows high-affinity binding to β-catenin with SPR Kd of 82 nM, enhances antigen presentation and activates cDC1 cells.

物理化学性质&存储条件

分子量	670.86
分子式	C37H50N8O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(3-((R)-3-(3-(4-(1H-pyrazol-4-yl)benzyl)-3-cyclopropylureido)piperidin-1-yl)phenoxy)-N-(2-(2-(2-aminoethyl)pyrrolidin-1-yl)-2-oxoethyl)-2-methylpropanamide

参考文献

1. Wenhua Zhu, et al. J Med Chem. 2024 Aug 8;67(15):12485-12520.