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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Fatty Acid Synthase-trans-C75
trans-C75

Chemical Structure : trans-C75

CAS No.: 191282-48-1

trans-C75 (FASN inhibitor trans-C75, trans C75)

货号: PC-43006Not For Human Use, Lab Use Only.

trans-C75 is an enantiomer of FASN inhibitor C75, which is a synthetic, slow-binding inhibitor of mammalian FAS, binds to and inhibits mammalian FAS and inhibits fatty acid synthesis in human cancer cells (SKBR3 cells ID50=3.2 ug/mL).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

trans-C75 is an enantiomer of FASN inhibitor C75, which is a synthetic, slow-binding inhibitor of mammalian FAS, binds to and inhibits mammalian FAS and inhibits fatty acid synthesis in human cancer cells (SKBR3 cells ID50=3.2 ug/mL).

物理化学性质&存储条件

分子量 254.3221
分子式 C14H22O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-Furancarboxylic acid, tetrahydro-4-methylene-2-octyl-5-oxo-, (2R,3S)-rel-

参考文献

1. Kuhajda FP, et al. Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3450-4.

2. Gao S, et al. Proc Natl Acad Sci U S A. 2003 May 13;100(10):5628-33.

3. Thupari JN, et al. Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9498-502.

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