pNPS90 | pBRD4 inhibitor | Probechem Biochemicals

Chemical Structure : pNPS90

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pNPS90 (pNPS-binding compound 90)

货号: PC-21994Not For Human Use, Lab Use Only.

pNPS90 is a small molecule inhibitor of phospho-BRD4 (pBRD4) with IC50 of 1.5 uM, binds to phospho-NPS (pNPS) and disrupts HPV E2-BRD4 interaction, effectively inhibits HPV ecDNA replication.

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生物&药学活性

pNPS90 is a small molecule inhibitor of phospho-BRD4 (pBRD4) with IC50 of 1.5 uM, binds to phospho-NPS (pNPS) and disrupts HPV E2-BRD4 interaction, effectively inhibits HPV ecDNA replication.

物理化学性质&存储条件

分子量	389.47
分子式	C22H19N3O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(6-Methoxy-1H-indol-3-yl)-4-(5-methoxy-2-methyl-1H-indol-3-yl)thiazole

参考文献

1. Wu SY, et al. Mol Cell. 2024 Jan 18;84(2):202-220.e15.

pNPS90 (pNPS-binding compound 90)

生物&药学活性

物理化学性质&存储条件

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pNPS90 (pNPS-binding compound 90)

生物&药学活性

物理化学性质&存储条件

参考文献

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