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myomiRs-IN-1

Chemical Structure : myomiRs-IN-1

CAS No.: 1392224-59-7

myomiRs-IN-1

货号: PC-62487Not For Human Use, Lab Use Only.

myomiRs-IN-1 is a small-molecule probe that selectively inhibits myogenic microRNAs (myomiRs) including miR-1, miR-133a, and miR-206.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    myomiRs-IN-1 is a small-molecule probe that selectively inhibits myogenic microRNAs (myomiRs) including miR-1, miR-133a, and miR-206.
    myomiRs-IN-1 upregulates miR-221/222 level and suppresses myoD protein expression in C2C12 cells.
    myomiRs-IN-1 inhibits the differentiation of C2C12 cells.

    物理化学性质&存储条件

    分子量 533.58
    分子式 C33H27NO6
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    tert-butyl (5-(8a-methoxy-3,8-dioxo-2-phenyl-2a,3,8,8a-tetrahydrocyclobuta[b]naphthalen-1-yl)quinolin-8-yl) carbonate

    参考文献

    1. Tan SB, et al. Chem Biol. 2014 Oct 23;21(10):1265-70.

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