miR544-IN-1 |CAS:522606-67-3 Probechem Biochemicals

Chemical Structure : miR544-IN-1

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miR544-IN-1 (SID 3712249)

货号: PC-62390Not For Human Use, Lab Use Only.

miR544-IN-1 (SID 3712249) is a selective small molecule inhibitor of miR-544 biogenesis.

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1 g		Get quote

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生物&药学活性

miR544-IN-1 (SID 3712249) is a selective small molecule inhibitor of miR-544 biogenesis; selectively inhibits production of the mature microRNA, sensitizes cells to 5-fluorouracil, and derepresses mRNAs affected by miR-544 in cellulo and in vivo, including boosting mTOR expression; reverses a tumor cell's physiological response to hypoxia.

物理化学性质&存储条件

分子量	323.404
分子式	C17H21N7
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1,8-diamino-3,6-di(pyrrolidin-1-yl)-2,7-naphthyridine-4-carbonitrile

参考文献

1. Haga CL, et al. ACS Chem Biol. 2015 Oct 16;10(10):2267-76.

miR544-IN-1 (SID 3712249)

生物&药学活性

物理化学性质&存储条件

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miR544-IN-1 (SID 3712249)

生物&药学活性

物理化学性质&存储条件

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