miR-21 inhibitor 12 | miR-21 inhibitor | Probechem Biochemicals

Chemical Structure : miR-21 inhibitor 12

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miR-21 inhibitor 12 (miR-21-IN-12)

货号: PC-73033Not For Human Use, Lab Use Only.

miR-21 inhibitor 12 (miR-21-IN-12) is a small molecule inhibitor of microRNA-21 expression and inhibit miR-21 transcription.

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生物&药学活性

miR-21 inhibitor 12 (miR-21-IN-12) is a small molecule inhibitor of microRNA-21 expression and inhibit miR-21 transcription.
miR-21-IN-12 inhibited transcription of the miR-21 gene resulting in significant reductions in primary and mature miR-21 levels.
miR-21-IN-12 demonstrated cytotoxicity in a cervical cancer cell line via induction of apoptosis and was capable of reducing microtumor formation in a long-term clonogenic assay.
miR-21-IN-12 shows some level of selectivity for miR-21 and is not a general miRNA pathway inhibitor.

物理化学性质&存储条件

分子量	408.838
分子式	C22H17ClN2O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-(5-Chlorobenzo[d]oxazol-2-yl)phenyl)-2-(4-methoxyphenoxy)acetamide

参考文献

1. Ankenbruck N, et al. Bioorg Med Chem. 2019 May 29. pii: S0968-0896(19)30047-1.

miR-21 inhibitor 12 (miR-21-IN-12)

生物&药学活性

物理化学性质&存储条件

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miR-21 inhibitor 12 (miR-21-IN-12)

生物&药学活性

物理化学性质&存储条件

参考文献

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