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首页-小分子抑制剂&激动剂-Epigenetics-MicroRNA-miR-21-IN-2
miR-21-IN-2

Chemical Structure : miR-21-IN-2

CAS No.: 304880-74-8

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miR-21-IN-2

货号: PC-26665Not For Human Use, Lab Use Only.

miR-21-IN-2 is a high-affinity miR-21 inhibitor, binds to the apical loop region of the pre-miR-21 hairpin with KD of 2.3 uM in 2-AP assays, inhibits the maturation of the microRNA hairpin by binding near the apical loop and preventing Dicer processing.

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5 mg ￥1380 In stock
10 mg ￥2180 In stock
25 mg ￥3580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

miR-21-IN-2 is a high-affinity miR-21 inhibitor, binds to the apical loop region of the pre-miR-21 hairpin with KD of 2.3 uM in 2-AP assays, inhibits the maturation of the microRNA hairpin by binding near the apical loop and preventing Dicer processing.

物理化学性质&存储条件

分子量 488.22
分子式 C22H20Br2N2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-(3,6-Dibromo-9H-carbazol-9-yl)-3-(o-tolylamino)propan-2-ol

参考文献

1. Connelly CM, et al. Discovery of Inhibitors of MicroRNA-21 Processing Using Small Molecule Microarrays. ACS Chem Biol. 2017;12(2):435-443.

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