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首页-小分子抑制剂&激动剂-Epigenetics-Histone Methyltransferase (HMTase)-iZMYND8-34
iZMYND8-34

Chemical Structure : iZMYND8-34

CAS No.: 1358901-59-3

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iZMYND8-34 (iZMYND 8-34)

货号: PC-24337Not For Human Use, Lab Use Only.

iZMYND8-34 is a small molecule inhibitor of histone reader zinc finger MYND-type containing 8 (ZMYND8), inhibits ZMYND8 histone recognition, effectively blocks neuroendocrine prostate cancer (NEPC) development.

规格 价格 库存 数量
10 mg ￥980 In stock
25 mg ￥1580 In stock
50 mg ￥2580 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

iZMYND8-34 is a small molecule inhibitor of histone reader zinc finger MYND-type containing 8 (ZMYND8) with IC50 of 0.66 uM, inhibits ZMYND8 histone recognition, effectively blocks neuroendocrine prostate cancer (NEPC) development.

物理化学性质&存储条件

分子量 449.42
分子式 C22H19N5O6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

9-(benzo[d][1,3]dioxol-5-yl)-2-(3-ethoxy-2-hydroxyphenyl)-7-methyl-8-oxo-8,9-dihydro-7H-purine-6-carboxamide

参考文献

1. Wang H, et al. Nat Cancer. 2025 Mar 18. doi: 10.1038/s43018-025-00928-z.

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