iGOT1-01 | GOT1 inhibitor | Probechem Biochemicals

Chemical Structure : iGOT1-01

CAS No.: 882256-55-5

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iGOT1-01 (iGOT 1-01)

货号: PC-35823Not For Human Use, Lab Use Only.

iGOT1-01 is a small molecule inhibitor of aspartate aminotransferase 1 (glutamate oxaloacetate transaminase 1 (GOT1)) with IC50 of 11.3 uM.

规格	价格	库存
5 mg	￥2180	In stock
10 mg	￥3580	In stock
25 mg	￥5580	In stock
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100 mg		Get quote

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生物&药学活性

iGOT1-01 is a small molecule inhibitor of aspartate aminotransferase 1 (glutamate oxaloacetate transaminase 1 (GOT1)) with IC50 of 11.3 uM.
Inhibition of GOT1 preferentially leads to accumulation of the M+4 aspartate isotopologue from 13C-glutamine in pancreatic cancer cells

物理化学性质&存储条件

分子量	320.396
分子式	C19H20N4O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(1H-indol-4-yl)-N-phenylpiperazine-1-carboxamide

参考文献

1. Holt MC, et al. Biochemistry. 2018 Nov 12. doi: 10.1021/acs.biochem.8b00914.

iGOT1-01 (iGOT 1-01)

生物&药学活性

物理化学性质&存储条件

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iGOT1-01 (iGOT 1-01)

生物&药学活性

物理化学性质&存储条件

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