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首页-小分子抑制剂&激动剂-PI3K/Akt/mTOR Pathway-PI3K-hSMG-1 inhibitor 11e
hSMG-1 inhibitor 11e

Chemical Structure : hSMG-1 inhibitor 11e

CAS No.: 1402452-10-1

hSMG-1 inhibitor 11e (hSMG-1-IN-11e)

货号: PC-35788Not For Human Use, Lab Use Only.

hSMG-1 inhibitor 11e is a potent, selective PI3K-related protein kinase hSMG-1 inhibitor with IC50 of <0.05 nM, >900-fold selectivity over mTOR, and no significant activity against CDK1/2.

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2 mg ¥1980 In stock
5 mg ¥3280 In stock
10 mg ¥5280 In stock
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纯度 & COA & 质检文件 纯度: 98.83% (HPLC) Select Batch:

生物&药学活性

hSMG-1 inhibitor 11e is a potent, selective PI3K-related protein kinase hSMG-1 inhibitor with IC50 of <0.05 nM, >900-fold selectivity over mTOR, and no significant activity against CDK1/2.

物理化学性质&存储条件

分子量 517.608
分子式 C26H27N7O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N,N,2-trimethyl-5-((4-(2-(4-(3-methylureido)phenyl)pyridin-4-yl)pyrimidin-2-yl)amino)benzenesulfonamide

参考文献

1. Gopalsamy A, et al. Bioorg Med Chem Lett. 2012 Nov 1;22(21):6636-41.

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