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首页-小分子抑制剂&激动剂-Others-Other Targets-dPTBD
dPTBD

Chemical Structure : dPTBD

CAS No.: 315702-90-0

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dPTBD

货号: PC-27582Not For Human Use, Lab Use Only.

dPTBD is a copper ionophore and cuproptosis inducer, promotes intracellular copper accumulation particularly in the mitochondria, leading to metabolic disruption and cuproptotic cell death, exhibits significant antitumor efficacy in KRAS-driven cancers both in vitro and in vivo.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

dPTBD is a copper ionophore and cuproptosis inducer, promotes intracellular copper accumulation particularly in the mitochondria, leading to metabolic disruption and cuproptotic cell death, exhibits significant antitumor efficacy in KRAS-driven cancers both in vitro and in vivo.

物理化学性质&存储条件

分子量 296.39
分子式 C16H16N4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N1,N1-dimethyl-N4-(4-(pyridin-2-yl)thiazol-2-yl)benzene-1,4-diamine

参考文献

1. Sun Y, et al. Cancer Lett. 2026 Aug 3:218773.

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