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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Cyclin-dependent Kinase (CDK)-dCeMM4
dCeMM4

Chemical Structure : dCeMM4

CAS No.: 1281683-44-0

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dCeMM4

货号: PC-21964Not For Human Use, Lab Use Only.

dCeMM4 is a small glue degrader, induces ubiquitination and degradation of cyclin K by prompting an interaction of CDK12-cyclin K with a CRL4B ligase complex.

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5 mg ￥1280 In stock
10 mg ￥1980 In stock
25 mg ￥3280 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

dCeMM4 is a small glue degrader, induces ubiquitination and degradation of cyclin K by prompting an interaction of CDK12-cyclin K with a CRL4B ligase complex.

物理化学性质&存储条件

分子量 337.41
分子式 C14H15N3O3S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-(5-Methylfuran-2-carbonyl)-N-(5-methylthiazol-2-yl)thiazolidine-4-carboxamide

参考文献

1. Mayor-Ruiz C, et al. Nat Chem Biol. 2020;16(11):1199-1207.

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