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首页-小分子抑制剂&激动剂-Others-Other Targets-cjoc42
cjoc42

Chemical Structure : cjoc42

CAS No.: 2171519-89-2

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cjoc42 (cjoc 42)

货号: PC-47073Not For Human Use, Lab Use Only.

cjoc42 is a specific small molecule that is capable of binding to gankyrin (ITC Kd=580 nM), inhibit gankyrin activity in a dose-dependent manner.

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5 mg ￥2180 In stock
10 mg ￥3480 In stock
25 mg ￥5580 In stock
50 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

cjoc42 is a specific small molecule that is capable of binding to gankyrin (ITC Kd=580 nM), inhibit gankyrin activity in a dose-dependent manner.
cjoc42 prevents the decrease in p53 protein levels normally associated with high amounts of gankyrin, and restores p53-dependent transcription and sensitivity to DNA damage.

物理化学性质&存储条件

分子量 415.464
分子式 C20H21N3O5S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Methyl 4-(4-(3-(tosyloxy)propyl)-1H-1,2,3-triazol-1-yl)benzoate

参考文献

1. Anasuya Chattopadhyay, et al. Sci Rep. 2016 Apr 5;6:23732.

2. D'Souza AM, et al. Front Pharmacol. 2021 Mar 4;12:580722.

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