cRIPGBM | Probechem Biochemicals

Chemical Structure : cRIPGBM chloride

CAS No.: 2361988-77-2

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cRIPGBM chloride (RIPGBM derivative cRIPGBM;RIPGBM-18)

货号: PC-36133Not For Human Use, Lab Use Only.

cRIPGBM (RIPGBM derivative cRIPGBM, RIPGBM-18) is a metabolite of RIPGBM induces apoptosis in GBM CSCs (EC50=68 nM in GBM 1 cells) by interacting with RIPK2 (Kd=2.3 uM).

规格	价格	库存
25 mg	￥1880	In stock
100 mg	￥4580	In stock
200 mg	￥7280	In stock
1 g		Get quote

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生物&药学活性

cRIPGBM (RIPGBM derivative cRIPGBM, RIPGBM-18) is a metabolite of RIPGBM induces apoptosis in GBM CSCs (EC50=68 nM in GBM 1 cells) by interacting with RIPK2 (Kd=2.3 uM).
cRIPGBM induces caspase 1-dependent apoptosis, reduces the formation of a prosurvival RIPK2/TAK1 complex and increases the formation of a proapoptotic RIPK2/caspase 1 complex.

物理化学性质&存储条件

分子量	446.90
分子式	C26H20ClFN2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	O=C(C1=C2[N+](CC3=CC=C(F)C=C3)=C(C)N1CC4=CC=CC=C4)C5=C(C=CC=C5)C2=O.[Cl-]

参考文献

1. Lucki NC, et al. Proc Natl Acad Sci U S A. 2019 Mar 7. pii: 201816626. doi: 10.1073/pnas.1816626116.

cRIPGBM chloride (RIPGBM derivative cRIPGBM;RIPGBM-18)

生物&药学活性

物理化学性质&存储条件

参考文献

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询单

cRIPGBM chloride (RIPGBM derivative cRIPGBM;RIPGBM-18)

生物&药学活性

物理化学性质&存储条件

参考文献

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