cIAP1 E3 ligase inhibitor D19-14 | CAS 2408483-59-8 Probechem Biochemicals

Chemical Structure : cIAP1 E3 ligase inhibitor D19-14

加入收藏

cIAP1 E3 ligase inhibitor D19-14 (cIAP1 inhibitor D19-14)

货号: PC-35676Not For Human Use, Lab Use Only.

cIAP1 E3 ligase inhibitor D19-14 (cIAP1 inhibitor D19-14) is an improved analog of D19, demonstrates significantly increased ability to inhibit cIAP1 autoubiquitination and reduce protein levels of c-MYC in vitro.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

cIAP1 E3 ligase inhibitor D19-14 (cIAP1 inhibitor D19-14) is an improved analog of D19, demonstrates significantly increased ability to inhibit cIAP1 autoubiquitination and reduce protein levels of c-MYC in vitro.
D19-14 is more potent in inhibiting the proliferation of cancer cells than D19.
D19-14 exhibits acceptable pharmacokinetics properties in vivo, effectively decreases the levels of c-MYC protein in tumors in cancer xenograft model.

物理化学性质&存储条件

分子量	385.456
分子式	C18H15N3O3S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-2-((2-(5,6-dimethoxybenzo[d]thiazol-2-yl)hydrazono)methyl)benzo[b]thiophen-3-ol

参考文献

1. Li H, et al. Proc Natl Acad Sci U S A. 2018 Sep 4. pii: 201807711.

cIAP1 E3 ligase inhibitor D19-14 (cIAP1 inhibitor D19-14)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

cIAP1 E3 ligase inhibitor D19-14 (cIAP1 inhibitor D19-14)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.