cGAS inhibitor XQ2B | cGAS inhibitor | Probechem Biochemicals

Chemical Structure : cGAS inhibitor XQ2B

CAS No.: 2104728-28-9

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cGAS inhibitor XQ2B (Cyclo(DPhe-ATRL-Dphe-PVRL))

货号: PC-26963Not For Human Use, Lab Use Only.

cGAS inhibitor XQ2B is potent, selective cyclopeptide inhibitor of Cyclic GMP-AMP synthase (cGAS), specifically binds to the DNA binding site of cGAS and blocks the binding of dsDNA with cGAS, subsequently inhibits dsDNA-induced liquid phase condensation and activation of cGAS, inhibits HSV-1-induced antiviral immune responses and enhances HSV-1 infection in vitro and in vivo.

规格	价格	库存
5 mg	￥1980	In stock
10 mg	￥2980	In stock
25 mg	￥4880	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

物理化学性质&存储条件

分子量	1201.46
分子式	C59H92N16O11
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Cyclo (D-Phe-Ala-Thr-Arg-Leu-D-Phe-Pro-Val-Arg-Leu)

参考文献

1. Wang X, et al. Nat Commun. 2023 Oct 2;14(1):6132.

cGAS inhibitor XQ2B (Cyclo(DPhe-ATRL-Dphe-PVRL))

生物&药学活性

物理化学性质&存储条件

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cGAS inhibitor XQ2B (Cyclo(DPhe-ATRL-Dphe-PVRL))

生物&药学活性

物理化学性质&存储条件

参考文献

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