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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Angiotensin-converting Enzyme (ACE)-Zofenoprilat
Zofenoprilat

Chemical Structure : Zofenoprilat

CAS No.: 75176-37-3

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Zofenoprilat

货号: PC-27008Not For Human Use, Lab Use Only.

Zofenoprilat is a potent, specific angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.7 nM, exerts cardioprotective and renoprotective effects by inhibiting angiotensin II expression and lowering blood pressure.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Zofenoprilat is a potent, specific angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.7 nM, exerts cardioprotective and renoprotective effects by inhibiting angiotensin II expression and lowering blood pressure.

物理化学性质&存储条件

分子量 325.44
分子式 C15H19NO3S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(2S,4S)-1-((S)-3-Mercapto-2-methylpropanoyl)-4-(phenylthio)pyrrolidine-2-carboxylic acid

参考文献

1. Ranadive SA, et al. Pharm Res. 1992;9(11):1480-1486.

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