Ziprasidone hydrochloride |CAS:122883-93-6 Probechem Biochemicals

Chemical Structure : Ziprasidone hydrochloride

CAS No.: 122883-93-6

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Ziprasidone hydrochloride (CP-88059 hydrochloride;CP88059 hydrochloride;CP 88059 hydrochloride)

货号: PC-43964Not For Human Use, Lab Use Only.

A full antagonist of D2 and 5-HT2A receptors with Ki of 6.8 and 0.6 nM, respectively.

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生物&药学活性

A full antagonist of D2 and 5-HT2A receptors with Ki of 6.8 and 0.6 nM, respectively; also is a partial agonist of 5-HT1A, and a partial antagonist of 5-HT2C and 5-HT1D receptors; exhibits potent antipsychotic activity in vivo.

Schizophrenia

Approved

物理化学性质&存储条件

分子量	449.3966
分子式	C21H22Cl2N4OS
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2H-Indol-2-one, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-, hydrochloride (1:1)

参考文献

1. Mattei C, et al. J Cent Nerv Syst Dis. 2011 Feb 15;3:1-16.

2. Seeger TF, et al. J Pharmacol Exp Ther. 1995 Oct;275(1):101-13.

3. Schotte A, et al. Psychopharmacology (Berl). 1996 Mar;124(1-2):57-73.

Ziprasidone hydrochloride (CP-88059 hydrochloride;CP88059 hydrochloride;CP 88059 hydrochloride)

生物&药学活性

物理化学性质&存储条件

参考文献

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Ziprasidone hydrochloride (CP-88059 hydrochloride;CP88059 hydrochloride;CP 88059 hydrochloride)

生物&药学活性

物理化学性质&存储条件

参考文献

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