Ziftomenib (KO-539) | Menin inhibitor | Probechem Biochemicals

Chemical Structure : Ziftomenib

CAS No.: 2134675-36-6

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Ziftomenib (KO-539, KO 539)

货号: PC-72438Not For Human Use, Lab Use Only.

Ziftomenib (KO-539) is a potent, highly selective, oral menin inhibitor, demonstrates encouraging clinical activity as monotherapy for relapsed/refractory NPM1-mutated (NPM1-m) and KMT2A-rearranged AML.

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5 mg	￥1580	In stock
10 mg	￥2480	In stock
25 mg	￥3980	In stock
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生物&药学活性

Ziftomenib (KO-539) is a potent, highly selective, oral menin inhibitor, demonstrates encouraging clinical activity as monotherapy for relapsed/refractory NPM1-mutated (NPM1-m) and KMT2A-rearranged AML.

物理化学性质&存储条件

分子量	717.875
分子式	C33H42F3N9O2S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1H-Indole-2-carbonitrile, 4-methyl-5-[[4-[[2-(methylamino)-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl]amino]-1-piperidinyl]methyl]-1-[(2S)-2-[4-(methylsulfonyl)-1-piperazinyl]propyl]-

参考文献

1. Cancer Discov. 2021 Feb;11(2):216-217.

Ziftomenib (KO-539, KO 539)

生物&药学活性

物理化学性质&存储条件

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Ziftomenib (KO-539, KO 539)

生物&药学活性

物理化学性质&存储条件

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