Zidebactam | β-lactam enhancer | Probechem Biochemicals

Chemical Structure : Zidebactam

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Zidebactam (WCK-5107, WCK5107)

货号: PC-23241Not For Human Use, Lab Use Only.

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250 mg		Get quote

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生物&药学活性

Zidebactam (WCK-5107) is a β-Lactam Enhancer, inhibitor of class A, class C and some class D β-lactamases with MIC of <2 ug/ mL for most Escherichia coli , Klebsiella , Citrobacter and Enterobacter spp., also binds to penicillin-binding protein2 (PBP2).
Zidebactam (WCK-5107) showed specific PBP2 inhibition and did not inhibit VIM-2.
Zidebactam (WCK-5107) exhibits direct antibacterial activity and a β-lactamase-independent 'enhancer' effect, potentiating β-lactams targeting PBP3.

物理化学性质&存储条件

分子量	391.40
分子式	C13H21N5O7S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(1R,2S,5R)-7-Oxo-2-(2-((R)-piperidine-3-carbonyl)hydrazine-1-carbonyl)-1,6-diazabicyclo[3.2.1]octan-6-yl hydrogen sulfate

参考文献

1. Moya B, et al. Antimicrob Agents Chemother. 2017 May 24;61(6):e02529-16.

2. Livermore DM, et al. J Antimicrob Chemother. 2017 May 1;72(5):1373-1385.

Zidebactam (WCK-5107, WCK5107)

生物&药学活性

物理化学性质&存储条件

参考文献

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Zidebactam (WCK-5107, WCK5107)

生物&药学活性

物理化学性质&存储条件

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