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首页-小分子抑制剂&激动剂-Epigenetics-Bromodomain-Zavabresib
Zavabresib

Chemical Structure : Zavabresib

CAS No.: 2089390-09-8

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Zavabresib (BET-IN-16)

货号: PC-25104Not For Human Use, Lab Use Only.

Zavabresib is a potent BET inhibitor with anticancer activity, inhibits prostate cancer cell growth with IC50 of 0.043 and 0.034 μM against LNCaP and 22Rv1 cells, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Zavabresib is a potent BET inhibitor with anticancer activity, inhibits prostate cancer cell growth with IC50 of 0.043 and 0.034 μM against LNCaP and 22Rv1 cells, respectively.

物理化学性质&存储条件

分子量 515.57
分子式 C31H25N5O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-(1-(1,1-di(pyridin-2-yl)ethyl)-6-(3,5-dimethylisoxazol-4-yl)-1H-pyrrolo[3,2-b]pyridin-3-yl)benzoic acid

参考文献

1. Patent US20170081326 A1.

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