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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Dopamine beta-hydroxylase-Zamicastat
Zamicastat

Chemical Structure : Zamicastat

CAS No.: 1080028-80-3

Zamicastat (BIA 5-1058)

货号: PC-22596Not For Human Use, Lab Use Only.

Zamicastat (BIA 5-1058) is a potent, selective dopamine β-hydroxylase (DβH) inhibitor, decreases noradrenaline and increases dopamine levels.

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10 mg ¥3280 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Zamicastat (BIA 5-1058) is a potent, selective dopamine β-hydroxylase (DβH) inhibitor, decreases noradrenaline and increases dopamine levels.

物理化学性质&存储条件

分子量 401.48
分子式 C21H21F2N3OS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-[(3R)-6,8-Difluoro-3,4-dihydro-2H-1-benzopyran-3-yl]-1,3-dihydro-5-[2-[(phenylmethyl)amino]ethyl]-2H-imidazole-2-thione

参考文献

1. Igreja B, et al. Eur J Pharmacol. 2019 Jan 5;842:125-132.

2. Bicker J, et al. Eur J Pharm Sci. 2018 May 30;117:35-40.

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