Zaloglanstat | mPGES-1 inhibitor | Probechem Biochemicals

Chemical Structure : Zaloglanstat

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Zaloglanstat (ISC-27864, GRC-27864)

货号: PC-38688Not For Human Use, Lab Use Only.

Zaloglanstat (ISC-27864, GRC-27864) is a potent, selective, non-opioid and orally active microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor, exhibits significant analgesic efficacy in preclinical models for osteoarthritis and inflammatory arthritis.

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生物&药学活性

Zaloglanstat (ISC-27864, GRC-27864) is a potent, selective, non-opioid and orally active microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor, exhibits significant analgesic efficacy in preclinical models for osteoarthritis and inflammatory arthritis.

物理化学性质&存储条件

分子量	452.862
分子式	C21H20ClF3N4O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-chloro-3-(5-oxo-1-(4-(trifluoromethyl)phenyl)-2,5-dihydro-1H-1,2,4-triazol-3-yl)benzyl)pivalamide

参考文献

1. Sant S, et al. Osteoarthritis Cartilage 2018, 26, S351– S352, DOI: 10.1016/j.joca.2018.02.698

Zaloglanstat (ISC-27864, GRC-27864)

生物&药学活性

物理化学性质&存储条件

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Zaloglanstat (ISC-27864, GRC-27864)

生物&药学活性

物理化学性质&存储条件

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