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首页-小分子抑制剂&激动剂-GPCR-Glucagon Receptor-Zabopegdutide
Zabopegdutide

Chemical Structure : Zabopegdutide

CAS No.: 2468152-46-5

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Zabopegdutide (DD01, DD-01)

货号: PC-26364Not For Human Use, Lab Use Only.

Zabopegdutide (DD01) is a potent, liver-targeted pegylated glucagon-like peptide-1 (GLP-1)/glucagon dual receptor agonist, shows potential for metabolic dysfunction-associated steatotic liver disease (MASLD) and MASH.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Zabopegdutide (DD01) is a potent, liver-targeted pegylated glucagon-like peptide-1 (GLP-1)/glucagon dual receptor agonist, shows potential for metabolic dysfunction-associated steatotic liver disease (MASLD) and MASH. 

    物理化学性质&存储条件

    分子量
    分子式 (C2H4O)n(C2H4O)n(C2H4O)nC176H259N43O56S2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    His-{Aib}-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-cylco{Glu-Gln-Ala-Ala-Lys}-Glu-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-{Cys-2,3-dimethyl ether-PEG450-520 N-(3-hydroxypropyl)carbamate-PEG50K-Mal}-NH2

    参考文献

    1. Noureddin M, et al. Lancet Gastroenterol Hepatol. 2026 Oct;11(10):887-896.

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