ZYZ-488 |CAS:1470302-79-4 Probechem Biochemicals

Chemical Structure : ZYZ-488

CAS No.: 1470302-79-4

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ZYZ-488 (ZYZ488)

货号: PC-62212Not For Human Use, Lab Use Only.

ZYZ-488 is a novel inhibitor of apoptotic protease activating factor-1 (Apaf-1), inhibits the activation of binding protein procaspase-9 and procaspase-3.

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5 mg	￥2980	In stock
10 mg	￥4780	In stock
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生物&药学活性

ZYZ-488 is a novel inhibitor of apoptotic protease activating factor-1 (Apaf-1), inhibits the activation of binding protein procaspase-9 and procaspase-3.
ZYZ-488 exhibits cardioprotective effects on hypoxia-induced H9c2 rat ventricular cells.
ZYZ-488 decreases apoptosis in hypoxic H9c2 cells, shows potential for treating cardiac ischemia.

物理化学性质&存储条件

分子量	487.462
分子式	C20H29N3O11
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S,3S,4S,5R,6S)-6-(4-((4-guanidinobutoxy)carbonyl)-2,6-dimethoxyphenoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid

参考文献

1. Wang Y, et al. Sci Rep. 2016 Jul 22;6:29820.

2. Wang Y, et al. Oxid Med Cell Longev. 2017;2017:9747296.

ZYZ-488 (ZYZ488)

生物&药学活性

物理化学性质&存储条件

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ZYZ-488 (ZYZ488)

生物&药学活性

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