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首页-小分子抑制剂&激动剂-Others-Other Targets-ZNF281 inhibitor ZIM
ZNF281 inhibitor ZIM

Chemical Structure : ZNF281 inhibitor ZIM

CAS No.:

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ZNF281 inhibitor ZIM (ZNF281 Interfering Molecule)

货号: PC-26553Not For Human Use, Lab Use Only.

ZNF281 inhibitor ZIM (ZNF281 Interfering Molecule) is a specific small molecule inhibitor of transcription factor ZNF281, prevents anthracycline-mediated cardiotoxicity (AIC), enhances lung tumor regression, and prevents lung metastasis in a metastatic melanoma model.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

ZNF281 inhibitor ZIM (ZNF281 Interfering Molecule) is a specific small molecule inhibitor of transcription factor ZNF281, prevents anthracycline-mediated cardiotoxicity (AIC), enhances lung tumor regression, and prevents lung metastasis in a metastatic melanoma model.

物理化学性质&存储条件

分子量 493.44
分子式 C20H13F6NO3S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(Z)-5-(4-((3,5-bis(trifluoromethyl)benzyl)oxy)-3-methoxybenzylidene)-2-thioxothiazolidin-4-one

参考文献

1. Lorenzana-Carrillo MA, et al. Sci Transl Med. 2026 Apr 15;18(845):eadz7727.

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