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首页-小分子抑制剂&激动剂-NF-κB Pathway-NF-κB-ZM600
ZM600

Chemical Structure : ZM600

CAS No.: 3030125-00-6

ZM600 (ZM 600, ZM-600)

货号: PC-22689Not For Human Use, Lab Use Only.

ZM600 is a novel antihepatic fibrosis compound that shows significant inhibitory effect on the activation of hepatic stellate cells (HSCs), specifically inhibits the activation of NF-κB, PI-3K/AKT, and TGF-β/Smads signaling pathways.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

ZM600 is a novel antihepatic fibrosis compound that shows significant inhibitory effect on the activation of hepatic stellate cells (HSCs), specifically inhibits the activation of NF-κB, PI-3K/AKT, and TGF-β/Smads signaling pathways.

物理化学性质&存储条件

分子量 506.66
分子式 C31H39FN2O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

methyl 4-((1R,3aR,3a1S,10aR)-2-(2-(2-fluoro-[1,1'-biphenyl]-4-yl)propanoyl)decahydro-1H,4H-pyrido[3,2,1-ij][1,6]naphthyridin-1-yl)butanoate

参考文献

1. Guoqing Li, et al. J Med Chem. 2024 Jul 11;67(13):11389-11400.

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