ZK-216348 |CAS:669073-68-1 Probechem Biochemicals

首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Glucocorticoid receptor (GR)-ZK-216348

Chemical Structure : ZK-216348

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ZK-216348 (ZK216348)

货号: PC-35001Not For Human Use, Lab Use Only.

ZK-216348 is a potent, selective, dissociated glucocorticoid receptor agonist with pIC50 of 7.7, shows selectivity over other nuclear hormone receptors.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ZK-216348 is a potent, selective, dissociated glucocorticoid receptor agonist with pIC50 of 7.7, shows selectivity over other nuclear hormone receptors.

物理化学性质&存储条件

分子量	476.45
分子式	C24H23F3N2O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(2,3-dihydro-1-benzofuran-7-yl)-2-hydroxy-4-methyl-N-(4-methyl-1-oxo-2,3-benzoxazin-6-yl)-2-(trifluoromethyl)pentanamide

参考文献

1. Schäcke H, et al. Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):227-32.

2. Jaroch S, et al. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5835-8.

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ZK-216348 (ZK216348)

生物&药学活性

物理化学性质&存储条件

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ZK-216348 (ZK216348)

生物&药学活性

物理化学性质&存储条件

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