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首页-小分子抑制剂&激动剂-Tyrosine Kinase-DYRK-ZJCK-6-72
ZJCK-6-72

Chemical Structure : ZJCK-6-72

CAS No.:

ZJCK-6-72

货号: PC-26800Not For Human Use, Lab Use Only.

ZJCK-6-72 is a highly potent, orally bioavailable, blood-brain barrier (BBB) permeable DYRK1A inhibitor with IC50 of 8.64 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

ZJCK-6-72 is a highly potent, orally bioavailable, blood-brain barrier (BBB) permeable DYRK1A inhibitor with IC50 of 8.64 nM.

物理化学性质&存储条件

分子量 421.50
分子式 C26H23N5O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-4-(6-(6-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)quinazolin-4-yl)-2-phenylmorpholine

参考文献

1. Zhenshu Li, et al. Front Pharmacol. 2026 May 1:17:1792258.

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