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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-iGluR-ZCAN155
ZCAN155

Chemical Structure : ZCAN155

CAS No.: 2485743-34-6

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ZCAN155 (ZCAN 155)

货号: PC-21624Not For Human Use, Lab Use Only.

ZCAN155 is a small molecule that prevents AMPA-mediated excitotoxicity (IC50=35 nM) by targeting an allosteric binding site of AMPA glutamate receptor 2 (GluA2), restores neurological function and myelination.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

ZCAN155 is a small molecule that prevents AMPA-mediated excitotoxicity (IC50=35 nM) by targeting an allosteric binding site of AMPA glutamate receptor 2 (GluA2), restores neurological function and myelination.

物理化学性质&存储条件

分子量 366.40
分子式 C19H19FN6O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(2-(4-fluorobenzyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl)-N,N-dimethylpyrimidine-4-carboxamide

参考文献

1. Zhai D, et al. Sci Adv. 2023 Dec 8;9(49):eadj6187.

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