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首页-小分子抑制剂&激动剂-Tyrosine Kinase-Syk-ZAP-70 inhibitor 20
ZAP-70 inhibitor 20

Chemical Structure : ZAP-70 inhibitor 20

CAS No.: 207284-01-3

ZAP-70 inhibitor 20

货号: PC-21066Not For Human Use, Lab Use Only.

ZAP-70 inhibitor 20 is a potent, selective ZAP-70 kinase inhibitor with IC50 of 8 nM, shows high selectivity over PKC, p56 Lck, EGFR and Csk.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

ZAP-70 inhibitor 20 is a potent, selective ZAP-70 kinase inhibitor with IC50 of 8 nM, shows high selectivity over PKC, p56 Lck, EGFR and Csk.

物理化学性质&存储条件

分子量 450.54
分子式 C24H30N6O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

COC1=C(OC)C(OC)=CC(NC2=NC=CC(C3=CC=C(N4C[C@H](CC)NCC4)N=C3)=N2)=C1

参考文献

1. D Moffat, et al. Bioorg Med Chem Lett. 1999 Dec 6;9(23):3351-6.

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