Z222979552 | SARS-CoV-2 Mpro inhibitor | Probechem Biochemicals

Chemical Structure : Z222979552

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Z222979552 (Z 222979552)

货号: PC-73013Not For Human Use, Lab Use Only.

Z222979552 is a small molecule non-covalent SARS-CoV-2 Mpro inhibitor with IC50 of 1.0 uM.

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生物&药学活性

Z222979552 is a small molecule non-covalent SARS-CoV-2 Mpro inhibitor with IC50 of 1.0 uM.
Z222979552 inhibits SARS-CoV-2 replication in Vero E6 cells in a dose-dependent manner, prevents the formation of dsRNA intermediates of SARS-CoV-2 RNA synthesis, with no cytotoxic effect.

物理化学性质&存储条件

分子量	392.20
分子式	C16H13IN2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-iodophenyl)-2-oxo-1,2,3,4-tetrahydroquinoline-4-carboxamide

参考文献

1. Rossetti GG, et al. Sci Rep. 2022 Feb 15;12(1):2505.

Z222979552 (Z 222979552)

生物&药学活性

物理化学性质&存储条件

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Z222979552 (Z 222979552)

生物&药学活性

物理化学性质&存储条件

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