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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Piezo Channel-Yoda1
Yoda1

Chemical Structure : Yoda1

CAS No.: 448947-81-7

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Yoda1 (Yoda 1, Yoda-1)

货号: PC-45542Not For Human Use, Lab Use Only.

Yoda1 is a potent, selective Piezo1 ion channel activator, affects the sensitivity and the inactivation kinetics of mechanically induced responses in cells.

规格 价格 库存 数量
5 mg ￥880 In stock
10 mg ￥1280 In stock
25 mg ￥2180 In stock
50 mg ￥3580 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Yoda1 is a potent, selective Piezo1 ion channel activator, affects the sensitivity and the inactivation kinetics of mechanically induced responses in cells.
Yoda1 activates purified Piezo1 channels in the absence of other cellular components.
Yoda1 potentiates shear-dependent platelet Ca2+ transients.

物理化学性质&存储条件

分子量 355.2654
分子式 C13H8Cl2N4S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 34 mg/mL
Chemical Name/SMILES

Pyrazine, 2-[5-[[(2,6-dichlorophenyl)methyl]thio]-1,3,4-thiadiazol-2-yl]-

参考文献

1. Syeda R, et al. Elife. 2015 May 22;4.

2. Ilkan Z, et al. J Biol Chem. 2017 Apr 17. pii: jbc.M116.766196.

3. Wang S, et al. J Clin Invest. 2016 Dec 1;126(12):4527-4536.

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