Yhhu-3792 |CAS:2097826-24-7 Probechem Biochemicals

Chemical Structure : Yhhu-3792

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Yhhu-3792 (Yhhu3792)

货号: PC-63504Not For Human Use, Lab Use Only.

Yhhu-3792 is a novel small molecule that enhances the self-renewal capability of neural stem cells (NSCs) in vitro and in vivo via activating the Notch signaling pathway.

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生物&药学活性

Yhhu-3792 is a novel small molecule that enhances the self-renewal capability of neural stem cells (NSCs) in vitro and in vivo via activating the Notch signaling pathway.
Yhhu-3792 activates Notch signaling pathway and promotes the expression of Notch target genes, Hes3 and Hes5.
Yhhu-3792 expands the NSCs pool and promotes endogenous neurogenesis in the hippocampal dentate gyrus (DG) after chronic administration in mice.

物理化学性质&存储条件

分子量	400.482
分子式	C24H24N4O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N2-(4-isopropylphenyl)-5-(3-methoxyphenoxy)quinazoline-2,4-diamine

参考文献

1. Hui L, et al. Stem Cells. 2018 May 3. doi: 10.1002/stem.2843.

Yhhu-3792 (Yhhu3792)

生物&药学活性

物理化学性质&存储条件

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Yhhu-3792 (Yhhu3792)

生物&药学活性

物理化学性质&存储条件

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