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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-HIV-YYA-021
YYA-021

Chemical Structure : YYA-021

CAS No.: 144217-65-2

YYA-021 (YYA021)

货号: PC-62898Not For Human Use, Lab Use Only.

YYA-021 is a small-molecule gp120-CD40 blocker that acts as a highly potent HIV entry inhibitor with IC50 of 9 uM against YTA48P virus with no significant cytotoxicity.

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10 mg ¥980 In stock
25 mg ¥1580 In stock
50 mg ¥2480 In stock
100 mg Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

YYA-021 is a small-molecule CD4-mimic and gp120-CD4 blocker that acts as a highly potent HIV entry inhibitor with IC50 of 9 uM against YTA48P virus with no significant cytotoxicity.
YYA-021 shows wide tissue distribution and relatively high distribution volumes, and has promise for intravenous administration.

物理化学性质&存储条件

分子量 317.433
分子式 C18H27N3O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N1-(4-methylphenyl)-N2-(2,2,6,6-tetramethyl-4-piperidinyl)-ethanediamide

参考文献

1. Hashimoto C, et al. Bioorg Med Chem. 2013 Dec 15;21(24):7884-9.

2. Otsuki H, et al. J Gen Virol. 2013 Dec;94(Pt 12):2710-6.

3. Narumi T, et al. Bioorg Med Chem. 2013 May 1;21(9):2518-26.

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