Chemical Structure : YYA-021
CAS No.: 144217-65-2
货号: PC-62898Not For Human Use, Lab Use Only.
YYA-021 is a small-molecule gp120-CD40 blocker that acts as a highly potent HIV entry inhibitor with IC50 of 9 uM against YTA48P virus with no significant cytotoxicity.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | ¥980 | In stock | |
25 mg | ¥1580 | In stock | |
50 mg | ¥2480 | In stock | |
100 mg | Get quote |
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YYA-021 is a small-molecule CD4-mimic and gp120-CD4 blocker that acts as a highly potent HIV entry inhibitor with IC50 of 9 uM against YTA48P virus with no significant cytotoxicity.
YYA-021 shows wide tissue distribution and relatively high distribution volumes, and has promise for intravenous administration.
分子量 | 317.433 | |
分子式 | C18H27N3O2 | |
外观性状 | Solid | |
储存条件 |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
N1-(4-methylphenyl)-N2-(2,2,6,6-tetramethyl-4-piperidinyl)-ethanediamide |
1. Hashimoto C, et al. Bioorg Med Chem. 2013 Dec 15;21(24):7884-9.
2. Otsuki H, et al. J Gen Virol. 2013 Dec;94(Pt 12):2710-6.
3. Narumi T, et al. Bioorg Med Chem. 2013 May 1;21(9):2518-26.
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