YT-III-31

Chemical Structure : YT-III-31

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货号: PC-28048Not For Human Use, Lab Use Only.

YT-III-31 is a selective positive allosteric modulator (PAM) of α3βγ2 GABAA receptor (GABAAR) with EC50 of 153 nM, Emax=917%.

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YT-III-31 is a selective positive allosteric modulator (PAM) of α3βγ2 GABAA receptor (GABAAR) with EC50 of 153 nM, Emax=917%.

分子量	340.39
分子式	C21H16N4O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	8-ethynyl-N-methyl-6-phenyl-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxamide

1. Batinić B, et al. Eur Neuropsychopharmacol. 2018 Aug;28(8):903-914.

2. Berro LF, et al. Alcohol Clin Exp Res. 2019 May;43(5):791-802.