YPC-22026 |CAS:1964457-41-7 Probechem Biochemicals

Chemical Structure : YPC-22026

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YPC-22026 (YPC22026)

货号: PC-62589Not For Human Use, Lab Use Only.

YPC-22026, a metabolically stable derivative of YPC-21661, is a novel small molecule inhibitor of the transcription factor Zinc-finger protein 143 (ZNF143), inhibits the binding of ZNF143 to DNA.

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生物&药学活性

YPC-22026, a metabolically stable derivative of YPC-21661, is a novel small molecule inhibitor of the transcription factor Zinc-finger protein 143 (ZNF143), inhibits the binding of ZNF143 to DNA.
YPC-22026 induces tumor regression accompanied by the suppression of ZNF143-regulated genes in a mouse xenograft model.

物理化学性质&存储条件

分子量	331.254
分子式	C16H8F3N3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(pyridine-3-ylethynyl)-5-(2-(trifluoromethoxy)phenyl)-1,3,4-oxadiazole

参考文献

1. Haibara H, et al. Cancer Sci. 2017 May;108(5):1042-1048.

YPC-22026 (YPC22026)

生物&药学活性

物理化学性质&存储条件

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YPC-22026 (YPC22026)

生物&药学活性

物理化学性质&存储条件

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