YM348 | 5-HT2C agonist | Probechem Biochemicals

Chemical Structure : YM348

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YM348 (YM-348)

货号: PC-27113Not For Human Use, Lab Use Only.

YM348 is a potent, selective and orally active 5-HT2C receptor agonist with Ki of 0.89 nM for cloned human 5-HT(2C) receptor.

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生物&药学活性

YM348 is a potent, selective and orally active 5-HT2C receptor agonist with Ki of 0.89 nM for cloned human 5-HT(2C) receptor.
Oral administration of YM348 induced penile erections and hypolocomotion in rats.
YM348 at 0.1, 0.3, 1 and 3 mg/kg significantly reduced food intake in a dose-dependent manner in Zucker rats.
YM348 dose-dependently and significantly increased body temperature in rats.

物理化学性质&存储条件

分子量	243.31
分子式	C14H17N3O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-(7-ethyl-1H-furo[2,3-g]indazol-1-yl)-1-methylethylamine

参考文献

1. Kimura Y, et al. Eur J Pharmacol. 2004 Jan 1;483(1):37-43.

2. Hayashi A, et al. Brain Res. 2004 Jun 18;1011(2):221-7.

3. Hayashi A, et al. J Pharm Pharmacol. 2004 Dec;56(12):1551-6.

YM348 (YM-348)

生物&药学活性

物理化学性质&存储条件

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YM348 (YM-348)

生物&药学活性

物理化学性质&存储条件

参考文献

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