YIR-819 TFA salt |CAS:1883372-87-9 Probechem Biochemicals

Chemical Structure : YIR-819 TFA salt

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YIR-819 TFA salt (YIR819 )

货号: PC-62778Not For Human Use, Lab Use Only.

YIR-819 is a small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 2.6 uM against YTA48P virus with no significant cytotoxicity (CC50=33 uM).

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100 mg		Get quote
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1 g		Get quote

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生物&药学活性

YIR-819 is a small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 2.6 uM against YTA48P virus with no significant cytotoxicity (CC50=33 uM); A useful lead compound for the further development of HIV-1 entry inhibitors and could potentially be useful for co-administration with neutralizing antibodies for the treatment of HIV infection and AIDS.

物理化学性质&存储条件

分子量	606.044
分子式	C25H35ClF3N7O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N1-(4-chlorophenyl)-N2-(1-(2-(2-guanidinoacetamido)ethyl)-1-azaspiro[5.5]undecan-4-yl)oxalamide TFA salt

参考文献

1. Ohashi N, et al. ChemMedChem. 2016 Apr 19;11(8):940-6.

2. Boonstra A, et al. Antivir Ther. 2012;17(4):657-67.

YIR-819 TFA salt (YIR819 )

生物&药学活性

物理化学性质&存储条件

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YIR-819 TFA salt (YIR819 )

生物&药学活性

物理化学性质&存储条件

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