YD1130

Chemical Structure : YD1130

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货号: PC-23237Not For Human Use, Lab Use Only.

YD1130 is a potent, selective PRMT4 inhibitor with IC50 of <1 nM, 1000-fold selectivity for PRMT4 (IC50 < 0.5 nM) over a panel of 38 methyltransferases, including the other PRMTs.

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生物&药学活性

YD1130 is a potent, selective PRMT4 inhibitor with IC50 of <1 nM, 1000-fold selectivity for PRMT4 (IC50 < 0.5 nM) over a panel of 38 methyltransferases, including the other PRMTs.

物理化学性质&存储条件

分子量	495.40
分子式	C19H23BrN6O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(3R,4R,5S)-2-(6-amino-9H-purin-9-yl)-5-(((2-((3-bromobenzyl)amino)ethyl)thio)methyl)tetrahydrofuran-3,4-diol

参考文献

1. Deng Y, et al. J Med Chem. 2024 Oct 3. doi: 10.1021/acs.jmedchem.4c01041.

YD1130

生物&药学活性

物理化学性质&存储条件

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YD1130

生物&药学活性

物理化学性质&存储条件

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