Chemical Structure : YCT-529
CAS No.: 2863670-67-9
货号: PC-23768Not For Human Use, Lab Use Only.
YCT-529 is a potent and selective RARα antagonist with IC50 of 6.8 nM, shows no activity against RARβ and RARγ up to 30 uM.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 mg | ¥2580 | In stock | |
| 10 mg | ¥3980 | In stock | |
| 25 mg | ¥5980 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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YCT-529 is a potent and selective RARα antagonist with IC50 of 6.8 nM, shows no activity against RARβ and RARγ up to 30 uM.
YCT-529 demonstrated excellent in vivo efficacy in inhibiting spermatogenesis and inducing infertility in mice, with fertility recovery following drug discontinuation.
| 分子量 | 457.50 | |
| 分子式 | C29H24NNaO3 | |
| 外观性状 | Solid | |
| 储存条件 |
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|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
Benzoic acid, 4-[5-[2,2-dimethyl-4-(4-methylphenyl)-2H-1-benzopyran-6-yl]-1H-pyrrol-2-yl]-, sodium salt |
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1. Shi R, et al. Contraception. 2025 Jan 3:110809.
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