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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-RAR/RXR-YCT-529
YCT-529

Chemical Structure : YCT-529

CAS No.: 2863670-67-9

YCT-529 (YCT529)

货号: PC-23768Not For Human Use, Lab Use Only.

YCT-529 is a potent and selective RARα antagonist with IC50 of 6.8 nM, shows no activity against RARβ and RARγ up to 30 uM.

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5 mg ¥2580 In stock
10 mg ¥3980 In stock
25 mg ¥5980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

YCT-529 is a potent and selective RARα antagonist with IC50 of 6.8 nM, shows no activity against RARβ and RARγ up to 30 uM.
YCT-529 demonstrated excellent in vivo efficacy in inhibiting spermatogenesis and inducing infertility in mice, with fertility recovery following drug discontinuation.

物理化学性质&存储条件

分子量 457.50
分子式 C29H24NNaO3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzoic acid, 4-[5-[2,2-dimethyl-4-(4-methylphenyl)-2H-1-benzopyran-6-yl]-1H-pyrrol-2-yl]-, sodium salt

参考文献

1. Shi R, et al. Contraception. 2025 Jan 3:110809.

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