Chemical Structure : YB-0158
CAS No.: 1144043-83-3
货号: PC-72907Not For Human Use, Lab Use Only.
YB-0158 (YB0158) is a β-turn peptidomimetic small molecule altering key hallmarks of human colorectal tumorigenesis, with high predicted affinity for Sam68.
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YB-0158 (YB0158) is a β-turn peptidomimetic small molecule altering key hallmarks of human colorectal tumorigenesis, with high predicted affinity for Sam68.
YB-0158 elicits a cancer-selective response impeding main cancer stem cell hallmarks .
YB-0158 blocks icolorectal cancer stem cell activity in tumor organoids and in vivo systems.
Sam68 is a putative target of β-turn peptidomimetic molecules in cancer cells.
分子量 | 705.61 | |
分子式 | C32H34N7O7P.2Na | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
2H-Pyrazino[2,1-c][1,2,4]triazine-1(6H)-carboxamide, hexahydro-8-(1H-indazol-7-ylmethyl)-4,7-dioxo-N-(phenylmethyl)-6-[[4-(phosphonooxy)phenyl]methyl]-2-(2-propen-1-yl)-, sodium salt (1:2), (6S,9aS)- |
1. Angelique N Masibag, et al. iScience. 2021 Nov 14;24(12):103442.
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