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首页-小分子抑制剂&激动剂-Epigenetics-Bromodomain-Y08207
Y08207

Chemical Structure : Y08207

CAS No.: 2450965-64-5

Y08207 (Y 08207)

货号: PC-22484Not For Human Use, Lab Use Only.

Y08207 is a potent, selective CBP/p300 bromodomain inhibitor with IC50 of 26.37 nM (CBP bromodomain) in HTRF assays.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Y08207 is a potent, selective CBP/p300 bromodomain inhibitor with IC50 of 26.37 nM (CBP bromodomain) in HTRF assays.

物理化学性质&存储条件

分子量 422.42
分子式 C22H19FN4O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-acetyl-N-(2-fluoro-5-(hydroxymethyl)-3-(1-methyl-1H-pyrazol-4-yl)phenyl)-7-hydroxyindolizine-1-carboxamide

参考文献

1. Qiuping Xiang, et al. J Med Chem. 2022 Jan 13;65(1):785-810.

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