Xeruborbactam isoboxil

Chemical Structure : Xeruborbactam isoboxil

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货号: PC-24194Not For Human Use, Lab Use Only.

Xeruborbactam isoboxil is the prodrug of xeruborbactam, an ultrabroad-spectrum beta-lactamase inhibitor, inhibits class A extended-spectrum beta-lactamases with IC50 of 1-3 nM, carbapenemases such as KPC (IC50, 2.9 nM), class C P99 (IC50, 22 nM).

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250 mg		Get quote

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生物&药学活性

物理化学性质&存储条件

分子量	322.10
分子式	C15H16BFO6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(isobutyryloxy)methyl (1aR,7bS)-5-fluoro-2-hydroxy-1,1a,2,7b-tetrahydrobenzo[e]cyclopropa[c][1,2]oxaborinine-4-carboxylate

参考文献

1. Hecker SJ, et al. J Med Chem. 2020 Jul 23;63(14):7491-7507.

2. Lomovskaya O, et al. Antimicrob Agents Chemother. 2021 May 18;65(6):e00210-21.