XMD16-5 |CAS:1345098-78-3 Probechem Biochemicals

Chemical Structure : XMD16-5

CAS No.: 1345098-78-3

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XMD16-5 (XMD 16-5)

货号: PC-42339Not For Human Use, Lab Use Only.

XMD16-5 is a potent Ack1 (TNK2) inhibitor with IC50 of 0.38 uM in ELISA assay.

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5 mg	￥980	In stock
10 mg	￥1580	In stock
25 mg	￥2580	In stock
50 mg	￥3980	In stock
100 mg		Get quote

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生物&药学活性

XMD16-5 is a potent Ack1 (TNK2) inhibitor with IC50 of 0.38 uM in ELISA assay.
XMD16-5 exhibits potent inhibition of growth of the TNK2 mutant expressing cell lines with IC50s of 16 nM and 77 nM for the D163E and R806Q mutations.

物理化学性质&存储条件

分子量	416.47566
分子式	C23H24N6O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 29 mg/mL
Chemical Name/SMILES	6H-Pyrimido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[4-(4-hydroxy-1-piperidinyl)phenyl]amino]-11-methyl-

参考文献

1. Miduturu CV, et al. Chem Biol. 2011 Jul 29;18(7):868-79.

2. Maxson JE, et al. Cancer Res. 2016 Jan 1;76(1):127-38.

XMD16-5 (XMD 16-5)

生物&药学活性

物理化学性质&存储条件

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XMD16-5 (XMD 16-5)

生物&药学活性

物理化学性质&存储条件

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