XL-001 |CAS:1426153-46-9 Probechem Biochemicals

首页-小分子抑制剂&激动剂-GPCR-Cannabinoid Receptor-XL-001

Chemical Structure : XL-001

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XL-001 (XL001)

货号: PC-35625Not For Human Use, Lab Use Only.

XL-001 (XL001) is a novel specific CB2 inverse agonist with Ki of 0.5 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

XL-001 (XL001) is a novel specific CB2 inverse agonist with Ki of 0.5 nM.
XL-001 inhibits in a dose-dependent fashion the fibrogenic response induced by CB2 overexpression, CB2 agonist or transforming growth factor-β1.
XL-001 ameliorates kidney injury, fibrosis and inflammation in both the obstruction and ischemia/reperfusion models.

物理化学性质&存储条件

分子量	438.586
分子式	C25H30N2O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-(diethylamino)benzyl)-4-methoxy-N-(p-tolyl)benzenesulfonamide

参考文献

1. Zhou L, et al. Kidney Int. 2018 Aug 6. pii: S0085-2538(18)30397-1.

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XL-001 (XL001)

生物&药学活性

物理化学性质&存储条件

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XL-001 (XL001)

生物&药学活性

物理化学性质&存储条件

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